 |
|
Simon Letarte
Area of Expertise
Mass spectrometry
Proteomics
Current Position
Senior Research Scientist
Degree
Ph.D in Analytical Chemistry, Université de Montréal, Québec, Canada, 2003
Research Interests
Coming from a mass spectrometry background, Simon likes to create robust platforms for biological research. His current focus is biomarker discovery using high-throughput label-free quantitation. Such a platform enables intelligent sequencing of differentially abundant peptides that can discriminate between disease states. Simon is currently studying cancer and diabetes.
He is also interested in multiple reaction monitoring (MRM), a targeted MS technique that enables a higher sensitivity and dynamic range by looking only at certain pairs of precursors-fragments.
Selected Publications
Stuart LM, Boulais J, Charriere GM, Hennessy EJ, Brunet S, Jutras I, Goyette G, Rondeau C, Letarte S, Huang H, Ye P, Morales F, Kocks C, Bader JS, Desjardins M, Ezekowitz RA. A systems biology analysis of the Drosophila phagosome. 2007. Nature 445: 96-101.
Vitek O, Brusniak M-Y, Campbell D, Eddes J, Garbutt A, Letarte S, Martin D, Mueller L, Zhang N, Watts J, Aebersold R. A Controlled Sample Mixture for Validation of Computational Tools for Label-free LC-MS based Proteomics; Molecular and Cellular Proteomics; SUBMITTED 2006
Letarte S, Morency D, Wilkes JG, and Bertrand MJ. Py-MAB-TOF Detection and Identification of Microorganisms in Urine. 2004. Journal of Analytical and Applied Pyrolysis 71,13-25.
Wilkes JG, Glover KL, Holcomb M, Rafii F, Cao X, Sutherland JB, McCarthy SA, Letarte S, Bertrand MJ. Defining and Using Microbiological Spectral Databases. 2002. Journal of the American Society for Mass Spectrometry 13: 875-877
|
|
|
home
