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Mi-Youn K. Brusniak
Area of Expertise
Computational Biologist: scientific software and algorithm developments and applications
Current Position
Senior Software Engineer
Degree
Ph.D. in Pharmaceutics, University of Texas, Austin, TX,
August 1996
Dissertation: "Development and Application of Software for Computer-Assisted Drug Design."
Research Interests
Dr. Mi-Youn Brusniak's current research focus is to develop and enhance bioinformatics software to analyze LC-MS based proteomics data. She is an architectural/workflow designer and coordinator for the Corra, TIQAM and ATAQS (Automated and Targeted Analysis with Quantitative SRM) software which are a framework and set of computational tools for high throughput discovery and validation for various biological system researches.
Selected Publications
Brusniak MY , Bodenmiller B , Campbell D , Cooke K , Eddes J , Garbutt A , Lau H, Letarte S , Mueller LN , Sharma V , Vitek O , Zhang N , Aebersold A, Watts JD. Corra: Computational framework and tools for LC-MS discovery and targeted mass spectrometry-based proteomics. 2008 BMC Bioinformatics, 9:542.
Mueller LN, Mi-Youn Brusniak, Mani DR, Aebersold R. An assessment of software solutions and applied LC-MS data types for quantitative LC-MS based proteomics studies. Journal of Proteome Res., 7 (01), 51-61 10.1021/pr700758r.
Mueller LM, Rinner O, Schmidt A, Letarte S, Bodenmiller B, Brusniak, M, Vitek O, Aebersold R., Mueller M. SuperHirn - a novel tool for high resolution LC-MS based peptide/protein. 2007. Proteomics, 7, 3470-3480.
Lange V, Malmstrom JA, Didion J, King NL, Johansson BP, Shafer J, Rameseder J, Wong C-H, Deutsch EW, Brusniak M-Y, Buhlmann P, Domon B, Aebersold R. Targeted quantitative analysis of Streptococcus pyogenes virulence factors by multiple reaction monitoring. 2008. Molecular & Cellular Proteomics 7(8), 1489.
Hamid Mirzaei, Mi-Youn Brusniak, Lukas N. Mueller, Simon Letarte, Julian D. Watts, Ruedi Aebersold, Halogenated-peptides as internal standards (H-PINS); Introduction of a MS-Based Internal Standard Set for Liquid Chromatography Mass Spectrometry Molecular & Cellular Proteomics 8:1934-1946,2009
Relevant Links
http://tools.proteomecenter.org/Corra/corra.html
http://tools.proteomecenter.org/TIQAM/TIQAM.html
http://tools.proteomecenter.org/ATAQS/ATAQS.html
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